Mr. Dave: what are the side effects of
niacin? The biggest and most common one is flushing. I actually got a little
flushing today from my own niacin drug. Back in the days, when you just took
regular niacin then, some people still do that. I tried it for a while, and I
remember I felt like I was a scalping victim, felt like my whole head was
blowing off with just this intense fire. And I had to stop. I mean I could not
take it. That is the most common thing. Now you’ll see YouTube comments on this
channel and other places where people say, oh, I love that flush. Well, if you
love it and you can do it, that’s great. So there’s been a lot of focus on trying
to decrease that flushing. One of them was a chemical called Laropiprant.
LAROPIPRANT. Laropiprant. I’m blanking on the name of the drug company (it’s Merck).
There was a drug company on their base on 42nd Street in Manhattan. One of the
well-known names. They had a Laropiprant- niacin combination. And they did a
world-class trial on it and expected to just you know do the victory lap with a
whole bunch of new sales. And it blew up. It didn’t work at all. And what actually
happened was it appears that Laropiprant, when it decreases the… when
it does away with the flush from niacin, also did away with whatever was
helping decrease the cardiovascular risk. So that didn’t work. So what did the
medical community do? Well, in America, the response of the medical community was
just to throw the baby out with the bathwater. They said, well, niacin
doesn’t work. No, it wasn’t that niacin doesn’t work. It was that niacin treated
with and combined with Laropiprant doesn’t work. There are a couple of
versions of niacin that we know does work. I’ve got financial arrangements
with either one of these groups. One of them is Rugby. RUGBY. And the other
one is Enduracin. ENDURACIN. We’re trying to develop something
with Enduracin because they have been the best tolerated product where we can make
it more easily available. You can get it right now on Amazon.
The thing about Enduracin is they have wax matrix process. So you get a wax
matrix within the pill, and you’ve got the little pockets of niacin within it.
So it slows that down. What happens? Reliably, you still get the niacin impact,
but it slows down the release. And I’m like all the other patients that I’ve
dealt with so far are using it except a few a few will still get intolerable
flushes. But the vast majority of them do like I do you get sort of a little flush
and tingle. Not much of a bad when it all happens every month or two and lasts
about five minutes and then you never notice it again. So that’s the big thing.
You can also get some gastrointestinal problems with niacin. One of my family
members had that problem, had to stop it. Robert Pinsky: does long-term use of
niacin caused liver damage? There’s a lot of focus on liver damage
and there it has been reported. Yes, you can’t see it, and yes, it’s more
associated with niacin where other chemicals have been added. Bottom line: at
the end of the day, it’s sort of like statins, it’s sort of like aspirin when
indicated. It’s sort of like driving a car, sort of like flying in an airplane.
You pay your money, you take your risks. If you don’t have any cardiovascular
risk, I don’t recommend thinking niacin because there are some problems
associated with it. But if you have significant Lp(a), I clearly would
recommend it. A lot of folks that have low HDL. Obviously, we want to focus on
the carbs in the diet. But niacin is the only thing that’s been shown… the only
supplement or there’s been no medication that increases HDL. But again niacin
increases. There’s nothing that has such an impact on our cholesterol panel
like as a supplement like niacin. So we use it a lot. I personally use it. There’s nothing like a community we saw
that in the Louisville event. People got together and started talking about how
they’ve had challenges and successes in preventing their own heart attack, stroke
or chronic disease. It became very clear that you don’t have to be a doc with a
full-time, 30-year career in preventive medicine to understand this and
successfully prevent heart attack, stroke – the number one killer and disablers of
people. You don’t have to be a physician to prevent eye disease, kidney disease.
All you have to do is think, listen, and become part of the community. Now, how do
you do that? Go to the membership login on our web page. And as you can see, you
can get right in. You have to sign up if you haven’t signed up already.
And I’ve already signed up. I’ve already gone in. It’s very simple, very easy to
understand in order to help encourage this after the success and the positive
emotion the positive impact that we’re seeing with these events, we’re saying,
look, we need to offer more of these services for free in order to help grow
this community. So you’ll see us starting to do draws for the webinar event, the
courses. We’ve got a book coming out in about a month. We’ll be offering that
even full-blown evaluations providing those for free for folks that again
helped us grow the community. So if you’d like to find out what the most recent
rules are for the most recent draw, just come to the membership page. Thank
you for your interest.